Simultaneous infection of the renal graft by BK virus and CMV: case report

  • Luis Roberto León Unidad de Trasplante Renal, Instituto de Trasplante y Alta Complejidad (ITAC)-Diaverum, Ciudad Autónoma de Buenos Aires https://orcid.org/0000-0001-6058-2514
  • María Fernanda Toniolo Servicio de Anatomía Patológica, Instituto de Trasplante y Alta Complejidad (ITAC)-Diaverum
  • Olga Elena Guardia Unidad de Trasplante Renal Instituto de Trasplante y Alta Complejidad (ITAC)-Diaverum
  • Javier Walther Unidad deTrasplante Renal Instituto de Trasplante y Alta Complejidad (ITAC)-Diaverum
  • Lorena Tana Unidad deTrasplante Renal Instituto de Trasplante y Alta Complejidad (ITAC)-Diaverum
Keywords: Coinfection; Citomegalovirus; BK virus; tubulointersticial nephritis

Abstract

Cytomegalovirus (CMV) and BK polyoma virus (BKV) coinfection is a severe and uncommon complication, manifested as tubulointerstitial nephritis in kidney grafts. Viral reactivations (CMV/BKV) cause renal dysfunction and are mainly related to the intensity of immunosuppression. We present 2 cases of renal transplant patients with CMV/BKV coinfection documented in renal biopsy. The gold standard for diagnosis is the identification of specific BKV/CMV inclusions by immunohistochemistry on histopathology.

Published
2023-06-22
How to Cite
1.
León LR, Toniolo MF, Guardia OE, Walther J, Tana L. Simultaneous infection of the renal graft by BK virus and CMV: case report. Rev Nefrol Dial Traspl. [Internet]. 2023Jun.22 [cited 2024Jul.16];43(02):112-8. Available from: http://revistarenal.org.ar/index.php/rndt/article/view/906
Issue
Vol. 43 No. 02 (2023)
Section
Case Report

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