CMV disease with gastrointestinal involvement in kidney transplantation. Report of a case

  • Juan de Dios López-González Gila Servicio de Nefrología, Hospital Universitario Virgen de las Nieves, Granada, España
  • María del Pilar Aguilar Jaldo Servicio de Medicina Interna, Hospital Universitario Clínico San Cecilio, Granada, España
  • Elena Clavero García Servicio de Nefrología, Hospital Universitario Virgen de las Nieves, Granada, España
  • María del Cármen Ruiz Fuentes Servicio de Nefrología, Hospital Universitario Virgen de las Nieves, Granada, España
Keywords: cytomegalovirus infection, colitis, monitoring, mortality, kidney transplantation

Abstract

Cytomegalovirus (CMV) is the most important pathogen causing opportunistic infections in renal allograft recipients. The development of CMV disease is associated with increased morbidity, a higher incidence of other opportunistic infections, loss of allografts, and death. Therefore, an effective strategy is required to prevent CMV disease after kidney transplantation. We present the case of a patient who suffers from a severe gastrointestinal condition due to the pathogen itself with subsequent adequate clinical evolution.

References

1) Kotton CN, Fishman JA. Viral infection in the renal transplant recipient. J Am Soc Nephrol. 2005;16(6):1758-74. doi: 10.1681/ASN.2004121113.

2) De Keyzer K, Van Laecke S, Peeters P, Vanholder R. Human cytomegalovirus and kidney transplantation: a clinician's update. Am J Kidney Dis. 2011;58(1):118-26. doi: 10.1053/j.ajkd.2011.04.010.

3) Helanterä I, Egli A, Koskinen P, Lautenschlager I, Hirsch HH. Viral impact on long-term kidney graft function. Infect Dis Clin North Am. 2010;24(2):339-71. doi: 10.1016/j.idc.2010.02.003.

4) Hanley PJ, Bollard CM. Controlling cytomegalovirus: helping the immune system take the lead. Viruses. 2014;6(6):2242-58. doi: 10.3390/v6062242.

5) Kotton CN, Kumar D, Caliendo AM, Asberg A, Chou S, Danziger-Isakov L, Humar A; Transplantation Society International CMV Consensus Group. Updated International Consensus Guidelines on the Management of Cytomegalovirus in Solid-Organ Transplantation. Transplantation. 2013;96(4):333-60. doi: 10.1097/TP.0b013e31829df29d.

6) Torre-Cisneros J, Aguado JM, Caston JJ, Almenar L, Alonso A, Cantisán S, et al.; Spanish Society of Transplantation (SET); Group for Study of Infection in Transplantation of the Spanish Society of Infectious Diseases and Clinical Microbiology (GESITRA-SEIMC); Spanish Network for Research in Infectious Diseases (REIPI). Management of cytomegalovirus infection in solid organ transplant recipients: SET/GESITRA-SEIMC/REIPI recommendations. Transplant Rev (Orlando). 2016;30(3):119-43. doi: 10.1016/j.trre.2016.04.001.

7) Kotton CN, Kumar D, Caliendo AM, Huprikar S, Chou S, Danziger-Isakov L, et al.; The Transplantation Society International CMV Consensus Group. The Third International Consensus Guidelines on the Management of Cytomegalovirus in Solid-organ Transplantation. Transplantation. 2018;102(6):900-31. doi: 10.1097/TP.0000000000002191.
Published
2021-12-06
How to Cite
1.
Juan de Dios L-GG, Aguilar Jaldo M del P, Clavero García E, Ruiz Fuentes M del C. CMV disease with gastrointestinal involvement in kidney transplantation. Report of a case. Rev Nefrol Dial Traspl. [Internet]. 2021Dec.6 [cited 2024Dec.21];41(4):282-4. Available from: http://revistarenal.org.ar/index.php/rndt/article/view/717
Section
Case Report