Hyperuricemia, chronic renal disease and renal transplant (part II)

  • Liliana Miriam Obregón Servicio de Trasplante Renal. CRAI Sur-HIGA Gral. San Martín, La Plata, Buenos Aires
  • Carlos Cobeñas Servicio de Nefrología, Hospital de Niños Sup. Sor María Ludovica, La Plata, Buenos Aires
  • Carlos Díaz Servicio de Nefrología, CEMIC, Buenos Aires
  • Gabriela Greco Programa de Abordaje Integral de la Enfermedad Renal Crónica (PAIERC), INCUCAI, Buenos Aires
  • Rosana Groppa Servicio de Nefrología, Hospital Italiano de Buenos Aires
  • Nora Imperiali Servicio de Nefrología, Hospital Italiano de Buenos Aires
  • Hugo Sergio Petrone Servicio de Trasplante Renal. CRAI Sur-HIGA Gral. San Martín, La Plata, Buenos Aires
  • Gervasio Soler Pujol Servicio de Nefrología, CEMIC, Buenos Aires
  • Marcelo Fabián Taylor Servicio de Trasplante Renal. CRAI Sur-HIGA Gral. San Martín, La Plata, Buenos Aires
  • Alicia Ester Elbert Centro de Enfermedades Renales e Hipertensión Arterial (CEREHA), Buenos Aires
Keywords: hyperuricemia, immunosuppressants agents, cardiovascular risk, renal transplant

Abstract

Hyperuricemia (HU) in renal transplant (RT) has been defined, like general population, with KDIGO Guides, as over 6 mg/dl values in women and 7 mg/dl in men. HU incidence in some populations are 28%, reaching 80% in Cyclosporine era (CSA).
HU is early observed after RT, risk factors associated with its development include: advanced age at the time of RT; gout history or preexisting HU; obesity; metabolic syndrome presence (MS); graft function deterioration; use of Inmunosuppression drugs, mainly cyclosporine (CSA); use of diuretics.

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Published
2016-06-01
How to Cite
1.
Obregón LM, Cobeñas C, Díaz C, Greco G, Groppa R, Imperiali N, Petrone HS, Soler Pujol G, Taylor MF, Elbert AE. Hyperuricemia, chronic renal disease and renal transplant (part II). Rev Nefrol Dial Traspl. [Internet]. 2016Jun.1 [cited 2024Nov.26];36(2):124-36. Available from: http://revistarenal.org.ar/index.php/rndt/article/view/67
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Review Article