Minimal change disease as an initial clinical feature of COVID-19 infection in a Latin-American kidney transplant patient
Keywords:
renal transplant, COVID-19, coronavirus, SARS-CoV-2, severe acute respiratory syndrome, acute kidney injury, minimal change disease
Abstract
COVID-19 disease is a systemic infection associated with renal damage leading to acute kidney injury with acute tubular necrosis and several types of podocytopathies. We report a clinical case in a kidney transplant patient diagnosed with COVID-19 disease, acute kidney injury and nephrotic syndrome. SARS-CoV 2 PCR results in nasal swab was positive and kidney was negative. Renal histopathologic findings described minimal change disease. So far, this case is the first clinical report of minimal change disease associated to COVID-19 in a kidney transplant patient.
References
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14) Husain-Syed F, Wilhelm J, Kassoumeh S, Birk HW, Herold S, Vadász I, et al. Acute kidney injury and urinary biomarkers in hospitalized patients with coronavirus disease-2019. Nephrol Dial Transplant. 2020;35(7):1271-4. doi: 10.1093/ndt/gfaa162.
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3)Lubetzky M, Aull MJ, Craig-Schapiro R, Lee JR, Marku-Podvorica J, Salinas T, et al. Kidney allograft recipients, immunosuppression, and coronavirus disease-2019: a report of consecutive cases from a New York City transplant center. Nephrol Dial Transplant. 2020;35(7):1250-61. doi: 10.1093/ndt/gfaa154.
4) Batlle D, Soler MJ, Sparks MA, Hiremath S, South AM, Welling PA, et al.; COVID-19 and ACE2 in Cardiovascular, Lung, and Kidney Working Group. Acute kidney injury in COVID-19: emerging evidence of a distinct pathophysiology. J Am Soc Nephrol. 2020;31(7):1380-3. doi: 10.1681/ASN.2020040419.
5) Kudose S, Batal I, Santoriello D, Xu K, Barasch J, Peleg Y, et al. Kidney biopsy findings in patients with COVID-19. J Am Soc Nephrol. 2020;31(9):1959-68. doi: 10.1681/ASN.2020060802.
6) Larsen CP, Bourne TD, Wilson JD, Saqqa O, Sharshir MA. Collapsing glomerulopathy in a patient with coronavirus disease 2019 (COVID-2019). Kidney Int Rep. 2020;5(6):935-9. doi: 10.1016/j.ekir.2020.04.002.
7) Lazareth H, Péré H, Binois Y, Chabannes M, Schurder J, Bruneau T, et al. COVID-19-related collapsing glomerulopathy in a kidney transplant recipient. Am J Kidney Dis. 2020;76(4):590-4. doi: 10.1053/j.ajkd.2020.06.009.
8) Ahn W, Bomback AS. Approach to diagnosis and management of primary glomerular diseases due to podocytopathies in adults: core curriculum 2020. Am J Kidney Dis. 2020;75(6):955-64. doi: 10.1053/j.ajkd.2019.12.019.
9) Wada T, Nangaku M. A circulating permeability factor in focal segmental glomerulosclerosis: the hunt continues. Clin Kidney J. 2015;8(6):708-15. doi: 10.1093/ckj/sfv090.
10) Lai Q, Spoletini G, Bianco G, Graceffa D, Agnes S, Rossi M, et al. SARS-CoV2 and immunosuppression: A double-edged sword. Transpl Infect Dis. 2020;22(6):e13404. doi: 10.1111/tid.13404.
11) Massoth LR, Desai N, Szabolcs A, Harris CK, Neyaz A, Crotty R, et al. Comparison of RNA in situ hybridization and immunohistochemistry techniques for the detection and localization of SARS-CoV-2 in human tissues. Am J Surg Pathol. 2021;45(1):14-24. doi: 10.1097/PAS.0000000000001563.
12) Lazareth H, Péré H, Binois Y, Chabannes M, Schurder J, Bruneau T, et al. COVID-19-related collapsing glomerulopathy in a kidney transplant recipient. Am J Kidney Dis. 2020;76(4):590-4. doi: 10.1053/j.ajkd.2020.06.009.
13) Sun DQ, Wang TY, Zheng KI, Targher G, Byrne CD, Chen YP, et al. Subclinical acute kidney injury in COVID-19 patients: a retrospective cohort study. Nephron. 2020;144(7):347-50. doi: 10.1159/000508502.
14) Husain-Syed F, Wilhelm J, Kassoumeh S, Birk HW, Herold S, Vadász I, et al. Acute kidney injury and urinary biomarkers in hospitalized patients with coronavirus disease-2019. Nephrol Dial Transplant. 2020;35(7):1271-4. doi: 10.1093/ndt/gfaa162.
Published
2021-06-22
How to Cite
1.
Camargo-Salamanca A, Pinto-Ramírez J, Orozco-de la Hoz C, García-López A, Patino-Jaramillo N, Girón-Luque F. Minimal change disease as an initial clinical feature of COVID-19 infection in a Latin-American kidney transplant patient. Rev Nefrol Dial Traspl. [Internet]. 2021Jun.22 [cited 2024Jul.16];41(2):125-9. Available from: http://revistarenal.org.ar/index.php/rndt/article/view/649
Section
Case Report
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