Obstructive acute kidney injury with maintenance of diuresis: a case of ureter bifidity

  • Francisca Gomes da Silva Nephrology Department, Hospital Doutor Nélio Mendonça, Funchal, Portugal
Keywords: percutaneous kidney biopsy; macroscopic hematuria; hydronephrosis; acute kidney injury; obstructive uropathy; diminution of urine flow; ureter bifidity

Abstract

Percutaneous kidney biopsy in transplanted kidneys remains an essential and commonly performed procedure required for diagnostic and prognostic information. Hemorrhage is the main complication of renal graft biopsy.
We report a case of a 47-year-old caucasian woman admitted to perform an ultrasound (US)-guided biopsy of the renal graft. Six hours later, she presented with macroscopic hematuria which improved after urethral catheterization and intravenous hydration. However the hematuria reappeared associated with anemia and worsening of the serum creatinine value. The US study, revealed hydronephrosis with high Doppler derived renal resistive index compatible with clot obstruction. Despite the vesical lavage with drainage of several clots, the patient rapidly progressed to hemorrhagic shock with worsening of renal function. Pelvic computed tomography (CT) revealed calyx and pelvis duplicity and ureter bifidity which merged into a single ureter and inserted into the right anterolateral wall of the bladder. The inferior ureter was enlarged due to an obstructive clot.
Most acute obstructive uropathies are associated with significant pain or the abrupt diminution of urine flow. The presence of ureter bifidity in the CT study explained the maintenance of significant diuresis despite obstruction, located only to the lower ureter but with sufficient functional impact to condition acute kidney injury (AKI).

References

1) Iversen P, Brun C. Aspiration biopsy of the kidney. Am J Med. 1951;11(3):324-30.

2) Mathew TH, Kincaid-Smith P, Eremin J, Marshall VC. Percutaneous needle biopsy of renal homografts. Med J Aust. 1968;1(1):6-7.

3) Tapia-Canelas C, Zometa R, López-Oliva MO, Jiménez C, Rivas B, Escuin F, et al. Complications associated with renal graft biopsy in transplant patients. Nefrología. 2014;34(1):115-9.

4) Ahmad I. Biopsy of the transplanted kidney. Semin Intervent Radiol. 2004;21(4):275-81.

5) Glassberg KI, Braren V, Duckett JW, Jacobs EC, King LR, Lebowitz RL, et al. Suggested terminology for duplex systems, ectopic ureters and ureteroceles. J Urol. 1984;132(6):1153-4.

6) Dahnert W. Radiology review manual. 6th ed. Philadelphia: Wolters Kluwer, Lippincott Williams Wilkins, 2007. xx, 1210 p.

7) Siomou E, Papadopoulou F, Kollios KD, Photopoulos A, Evagelidou E, Androulakakis P, et al. Duplex collecting system diagnosed during the first 6 years of life after a first urinary tract infection: a study of 63 children. J Urol. 2006;175(2):678-81; discussion 681-2.

8) Bhamani A, Srivastava M. Obstructed bifid uretereric system causing unilateral hydronephrosis. Rev Urol. 2013;15(3):131-4.

9) Morgan TA, Chandran S, Burger IM, Zhang CA, Goldstein RB. Complications of ultrasound-guided renal transplant biopsies. Am J Transplant. 2016;16(4):1298-305.

10) de la Rosette JJ, Witjes WP, Schäfer W, Abrams P, Donovan JL, Peters TJ, et al. Relationships between lower urinary tract symptoms and bladder outlet obstruction: results from the ICS-"BPH" study. Neurourol Urodyn. 1998;17(2):99-108.

11) Bellomo R, Kellum JA, Ronco C. Acute kidney injury. Lancet. 2012;380(9843):756-66.

12) Streeter EH, Little DM, Cranston DW, Morris PJ. The urological complications of renal transplantation: a series of 1535 patients. BJU Int. 2002;90(7):627-34.

13) Duty BD, Barry JM. Diagnosis and management of ureteral complications following renal transplantation. Asian J Urol. 2015;2(4):202-7.

14) Berger PM, Diamond JR. Ureteral obstruction as a complication of renal transplantation: a review. J Nephrol. 1998;11(1):20-3.

15) Karam G, Hétet JF, Maillet F, Rigaud J, Hourmant M, Soulillou JP, et al. Late ureteral stenosis following renal transplantation: risk factors and impact on patient and graft survival. Am J Transplant. 2006;6(2):352-6.

16) Kasiske BL, Snyder JJ, Gilbertson DT, Wang C. Cancer after kidney transplantation in the United States. Am J Transplant. 2004;4(6):905-13.
Published
2020-08-13
How to Cite
1.
Gomes da Silva F. Obstructive acute kidney injury with maintenance of diuresis: a case of ureter bifidity. Rev Nefrol Dial Traspl. [Internet]. 2020Aug.13 [cited 2024Jul.16];39(4):905-13. Available from: http://revistarenal.org.ar/index.php/rndt/article/view/499
Section
Images in Nephrology