Hyperuricemia management in patients from Argentina. A questionnaire survey

  • Guillermo A. De’Marziani Centro de Enfermedades Renales e Hipertensión Arterial (CEREHA), Buenos Aires
  • Teresa Bensusán Comité de Nefropatía Diabética, Sociedad Argentina de Diabetes (SAD), Buenos Aires
  • María Estela Canda Comité de Nefropatía Diabética, Sociedad Argentina de Diabetes (SAD), Buenos Aires
  • Yanina M. Castaño Comité de Nefropatía Diabética, Sociedad Argentina de Diabetes (SAD), Buenos Aires
  • Fabiana Davila Servicio de Diabetología, Hospital Universitario Austral, Buenos Aires
  • Guillermo Dieuzeide Centro de Atención Integral en Diabetes, Endocrinología y Metabolismo, Servicio de Endocrinología y Diabetes, Hospital Nuestra Señora del Carmen, Chacabuco, Buenos Aires
  • Claudio Daniel González Departamento de Farmacología, Escuela de Medicina, Centro de Educación Médica e Investigaciones Clínicas Norberto Quirno (CEMIC), Buenos Aires
  • Paula Iscoff Servicio de Nefrología, Hospital Interzonal General de Agudos Presidente Perón, Buenos Aires
  • Yanina V. Maccio Servicio de Nefrología y Diálisis, Centro Integral de Medicina de Alta Complejidad (CIMAC), San Juan
  • Estrella Menéndez Servicio Nutrición y Diabetes, Centro de Educación Médica e Investigaciones Clínicas Norberto Quirno (CEMIC), Buenos Aires
  • Elisa Morales Fresenius Medical Care, Neuquén
  • Liliana Obregon Servicio de Trasplante Renal. CRAI Sur-HIGA Gral. San Martín, La Plata, Buenos Aires
  • María J. Pomares Centro de Enfermedades Renales e Hipertensión Arterial (CEREHA), Buenos Aires
  • Jimena Soutelo Servicio de Endocrinología, Hospital Médico Policial Churruca-Visca, Buenos Aires
  • Fabiana P. Vázquez Servicio de Endocrinología, Metabolismo, Nutrición y Diabetes, Hospital Británico, Buenos Aires
  • Gloria Viñes Servicio de Nutrición y Diabetes, Hospital Privado de Comunidad (HPC), Buenos Aires
  • Alicia E. Elbert Centro de Enfermedades Renales e Hipertensión Arterial (CEREHA), Buenos Aires
Keywords: uric acid, hyperuricemia, diabetes mellitus, chronic kidney disease, cardiovascular disease, gout, survey

Abstract

Introduction: For many years, uric acid was considered to be an inert product of purine metabolism; however, it has recently been associated with a number of chronic diseases. Nowadays, there are no conclusive findings available regarding a clear action plan to treat serum uric acid or which specific therapeutic goals it would have. Methods: Given this controversy, a survey was conducted in order to evaluate which decisions are taken regarding this situation within the Argentinian medical community. The question was in which cases serum uric acid was routinely assessed and the result was 53.2% no matter the pathology; 11% of physicians did not assess it routinely. Regarding its treatment, 62.5% of them reported to have treated it as part of kidney disease; 61.7 % as part of diabetes; 60.4% as part of metabolic syndrome; 50.3% as part of cardiovascular disease; 91.3 % as part of gout; 74% as part of renal stones, and 36.1% as part of joint pain. Results: The data collected by means of the survey show a lack of evidence for establishing the patient selection criteria when evaluating levels of serum uric acid and its treatment. Conclusions: Therefore, it is concluded that it is necessary to conduct prospective and randomized studies of conditions with a high incidence of elevated uricemia in order to develop guidelines for specialists according to results; this decision should not be based on experts’ opinion alone.

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Published
2019-09-19
How to Cite
1.
De’Marziani GA, Bensusán T, Canda ME, Castaño YM, Davila F, Dieuzeide G, González CD, Iscoff P, Maccio YV, Menéndez E, Morales E, Obregon L, Pomares MJ, Soutelo J, Vázquez FP, Viñes G, Elbert AE. Hyperuricemia management in patients from Argentina. A questionnaire survey. Rev Nefrol Dial Traspl. [Internet]. 2019Sep.19 [cited 2024Dec.25];39(3):175-83. Available from: http://revistarenal.org.ar/index.php/rndt/article/view/462
Issue
Vol. 39 No. 3 (2019): Jul.-Sept.
Section
Original Article