Estimated glomerular filtration rate in a sample of university students. Argentina, 2014-2015. Preliminary results

  • Cecilia Brissón Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Santa Fe
  • Ángela Pedro Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Santa Fe
  • Verónica Cuestas Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Santa Fe
  • Priscila Prono Minella Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Santa Fe
  • Rosina Bonifacino Belzarena Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Santa Fe
  • Verónica Fernández Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Santa Fe
  • Susana Denner Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Santa Fe
  • Silvia Marsili Facultad de Ciencias Médicas, Universidad Nacional del Litoral, Santa Fe
  • María Eugenia Brissón Universidad Nacional de Lanús, Buenos Aires
Keywords: glomerular filtration rate, chronic kidney disease, glomerular filtration rate categories, method comparison

Abstract

Introduction: The high global prevalence of Chronic Kidney Disease (CKD) and its implications for public health are well recognized. There are few studies related to the values of glomerular filtration rate (GFR) and its staging in young people. GFR was estimated by creatinine clearance (CrCl) by formulas, totals, by category G of GFR and sex on a sample of Argentine students. Agreement between estimation methods was also evaluated. Methods: Descriptive study of 75 students during the period May 2014-September 2015. GFR was estimated by Cockcroft-Gault (CG), MDRD-4 and CrCl using creatinine not traceable by IDMS and MDRD-4 IDMS and CKD-EPI with traceable creatinine. Results: Mean values and frequencies depending on the estimation method. Moderate to good agreement between CKD-EPI and CG and between CrCl and CGwas found. Conclusions: Although these findings are preliminary and should be confirmed in a larger sample, they help to describe higher GFR stages in a young population and to visualize differences between estimators used.

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Published
2017-04-25
How to Cite
1.
Brissón C, Pedro Ángela, Cuestas V, Prono Minella P, Bonifacino Belzarena R, Fernández V, Denner S, Marsili S, Brissón ME. Estimated glomerular filtration rate in a sample of university students. Argentina, 2014-2015. Preliminary results. Rev Nefrol Dial Traspl. [Internet]. 2017Apr.25 [cited 2024Nov.25];35(4):196-01. Available from: http://revistarenal.org.ar/index.php/rndt/article/view/41
Section
Original Article