Non invasive characterization of arterial stiffness in chronic renal failure patients in Hemodialysis

  • Rodolfo Valtuille Facultad Regional Buenos Aires, Universidad Tecnológica Nacional, Buenos Aires
  • Sebastián Graf Universidad Favaloro, Buenos Aires
  • Cintia Galli Facultad Regional Buenos Aires, Universidad Tecnológica Nacional, Buenos Aires
  • Walter Barmak Universidad Favaloro, Buenos Aires
  • Claudia Abelleira Fresenius Medical Care Burzaco, Buenos Aires
  • Myrna Tetta Fresenius Medical Care Burzaco, Buenos Aires
  • Edmundo Cabrera Fischer Universidad Favaloro, Buenos Aires
  • Daniel Bia Departamento de Fisiología, Facultad de Medicina, Universidad de la República, Montevideo
  • Ricardo Armentano Facultad Regional Buenos Aires, Universidad Tecnológica Nacional, Buenos Aires
Keywords: aortic stiffness, pulse wave velocity, hemodiálisis, renal dialysis

Abstract

Arterial stiffening is a common finding in patients on chronical hemodialysis (CHD) impairing the prognosis. The aim of this work was to characterize aortic stiffness through pulse wave velocity (PWV) determinations in a population of patients on CHD. For this purpose PWV, arterial pressure and biochemical and antropometric parameters were measured in 70 patients on CHD. Blood was always obtained and routine chemistry profiles were performed using standard techniques.
Parathyroid hormone serum levels, hemoglobin, cholesterol, total triglycerides, calcium, phosphates and albumin were determined. The body mass index (BMI) and the waist to hip ratio were calculated for each patient. We found that PWV mean value, measured in the carotid-femoral pathway, was abnormally increased (13.66±3.25 m/s) in patients on CHD respect to normal values (10.62±1.49 m/s) previously reported (P<0.05). Patients on CHD aged 60 y. o. or younger showed PWV values lower than those aged 61 y. o. or older (12.24±2.88 and 15.08±3.01 m/s; respectively, P<0.0001). Non diabetic patients on CHD showed PWV values lower than diabetic patients on CHD (13.30±3.13 and 15.57±3.40 m/s; respectively, P<0.0330). Systolic pressure values of 119 mmHg or lower showed decreased values of PWV than those with values of 120 mmHg or higher (12.43±3.27 and 14.38±3.06 m/s; respectively, P<0.0144) and patients with pulse pressure lower or equal to 40 mmHg showed decreased values of PWV than those with pulse pressure higher or equal to 41 mmHg (12.42±3.19 and 14.22±3.16 m/s; respectively, P<0.0302). We concluded that, in the analyzed CHD patients, there is an increase of arterial stiffness evaluated through PWV measurements. This increase was higher in diabetic patients, subjects 61 y. o. or older
and in those with arterial pressure of 120 mmHg or higher.

 

How to cite this article:

Valtuille R, Graf S, Galli C, Barmak W, Abelleira C, Tetta M, Cabrera Fischer E, Bia D, Armentano R. [Non invasive characterization of arterial stiffness in chronic renal failure patients in Hemodialysis]. Rev Nefrol Dial Traspl. 2009;29(1):29-34.

Published
2018-07-24
How to Cite
1.
Valtuille R, Graf S, Galli C, Barmak W, Abelleira C, Tetta M, Cabrera Fischer E, Bia D, Armentano R. Non invasive characterization of arterial stiffness in chronic renal failure patients in Hemodialysis. Rev Nefrol Dial Traspl. [Internet]. 2018Jul.24 [cited 2024Dec.23];29(1):29-4. Available from: http://revistarenal.org.ar/index.php/rndt/article/view/321
Issue
Vol. 29 No. 1 (2009): Ene.-Mar.
Section
Original Article