Enfermedad de cambios mínimos como manifestación inicial de COVID-19 en paciente latinoamericano con trasplante renal
Palabras clave:
trasplante de riñón, COVID-19, coronavirus, síndrome respiratorio agudo severo, SARS-CoV-2, lesión renal aguda, enfermedad cambios mínimos
Resumen
COVID-19 tiene un espectro amplio de manifestaciones clínicas, se ha descrito lesión renal aguda con evidencia de necrosis tubular aguda y diversos tipos de podocitopatías. Se presenta el caso clínico de un paciente con trasplante renal y COVID-19 que debuta con lesión renal aguda y síndrome nefrótico. Proteína C-reactiva para síndrome respiratorio agudo severo 2 en hisopado nasal es positiva y en tejido renal es negativa. Biopsia renal reporta enfermedad de cambios mínimos. A la fecha es el primer reporte de esta podocitopatía asociada a COVID-19 en paciente con trasplante renal.
Citas
1) Ronco C, Reis T, Husain-Syed F. Management of acute kidney injury in patients with COVID-19. Lancet Respir Med. 2020;8(7):738-42. doi: 10.1016/S2213-2600(20)30229-0.
2) Hong D, Long L, Wang AY, Lei Y, Tang Y, Zhao JW, et al. Kidney manifestations of mild, moderate and severe coronavirus disease 2019: a retrospective cohort study. Clin Kidney J. 2020;13(3):340-6. doi: 10.1093/ckj/sfaa083.
3)Lubetzky M, Aull MJ, Craig-Schapiro R, Lee JR, Marku-Podvorica J, Salinas T, et al. Kidney allograft recipients, immunosuppression, and coronavirus disease-2019: a report of consecutive cases from a New York City transplant center. Nephrol Dial Transplant. 2020;35(7):1250-61. doi: 10.1093/ndt/gfaa154.
4) Batlle D, Soler MJ, Sparks MA, Hiremath S, South AM, Welling PA, et al.; COVID-19 and ACE2 in Cardiovascular, Lung, and Kidney Working Group. Acute kidney injury in COVID-19: emerging evidence of a distinct pathophysiology. J Am Soc Nephrol. 2020;31(7):1380-3. doi: 10.1681/ASN.2020040419.
5) Kudose S, Batal I, Santoriello D, Xu K, Barasch J, Peleg Y, et al. Kidney biopsy findings in patients with COVID-19. J Am Soc Nephrol. 2020;31(9):1959-68. doi: 10.1681/ASN.2020060802.
6) Larsen CP, Bourne TD, Wilson JD, Saqqa O, Sharshir MA. Collapsing glomerulopathy in a patient with coronavirus disease 2019 (COVID-2019). Kidney Int Rep. 2020;5(6):935-9. doi: 10.1016/j.ekir.2020.04.002.
7) Lazareth H, Péré H, Binois Y, Chabannes M, Schurder J, Bruneau T, et al. COVID-19-related collapsing glomerulopathy in a kidney transplant recipient. Am J Kidney Dis. 2020;76(4):590-4. doi: 10.1053/j.ajkd.2020.06.009.
8) Ahn W, Bomback AS. Approach to diagnosis and management of primary glomerular diseases due to podocytopathies in adults: core curriculum 2020. Am J Kidney Dis. 2020;75(6):955-64. doi: 10.1053/j.ajkd.2019.12.019.
9) Wada T, Nangaku M. A circulating permeability factor in focal segmental glomerulosclerosis: the hunt continues. Clin Kidney J. 2015;8(6):708-15. doi: 10.1093/ckj/sfv090.
10) Lai Q, Spoletini G, Bianco G, Graceffa D, Agnes S, Rossi M, et al. SARS-CoV2 and immunosuppression: A double-edged sword. Transpl Infect Dis. 2020;22(6):e13404. doi: 10.1111/tid.13404.
11) Massoth LR, Desai N, Szabolcs A, Harris CK, Neyaz A, Crotty R, et al. Comparison of RNA in situ hybridization and immunohistochemistry techniques for the detection and localization of SARS-CoV-2 in human tissues. Am J Surg Pathol. 2021;45(1):14-24. doi: 10.1097/PAS.0000000000001563.
12) Lazareth H, Péré H, Binois Y, Chabannes M, Schurder J, Bruneau T, et al. COVID-19-related collapsing glomerulopathy in a kidney transplant recipient. Am J Kidney Dis. 2020;76(4):590-4. doi: 10.1053/j.ajkd.2020.06.009.
13) Sun DQ, Wang TY, Zheng KI, Targher G, Byrne CD, Chen YP, et al. Subclinical acute kidney injury in COVID-19 patients: a retrospective cohort study. Nephron. 2020;144(7):347-50. doi: 10.1159/000508502.
14) Husain-Syed F, Wilhelm J, Kassoumeh S, Birk HW, Herold S, Vadász I, et al. Acute kidney injury and urinary biomarkers in hospitalized patients with coronavirus disease-2019. Nephrol Dial Transplant. 2020;35(7):1271-4. doi: 10.1093/ndt/gfaa162.
2) Hong D, Long L, Wang AY, Lei Y, Tang Y, Zhao JW, et al. Kidney manifestations of mild, moderate and severe coronavirus disease 2019: a retrospective cohort study. Clin Kidney J. 2020;13(3):340-6. doi: 10.1093/ckj/sfaa083.
3)Lubetzky M, Aull MJ, Craig-Schapiro R, Lee JR, Marku-Podvorica J, Salinas T, et al. Kidney allograft recipients, immunosuppression, and coronavirus disease-2019: a report of consecutive cases from a New York City transplant center. Nephrol Dial Transplant. 2020;35(7):1250-61. doi: 10.1093/ndt/gfaa154.
4) Batlle D, Soler MJ, Sparks MA, Hiremath S, South AM, Welling PA, et al.; COVID-19 and ACE2 in Cardiovascular, Lung, and Kidney Working Group. Acute kidney injury in COVID-19: emerging evidence of a distinct pathophysiology. J Am Soc Nephrol. 2020;31(7):1380-3. doi: 10.1681/ASN.2020040419.
5) Kudose S, Batal I, Santoriello D, Xu K, Barasch J, Peleg Y, et al. Kidney biopsy findings in patients with COVID-19. J Am Soc Nephrol. 2020;31(9):1959-68. doi: 10.1681/ASN.2020060802.
6) Larsen CP, Bourne TD, Wilson JD, Saqqa O, Sharshir MA. Collapsing glomerulopathy in a patient with coronavirus disease 2019 (COVID-2019). Kidney Int Rep. 2020;5(6):935-9. doi: 10.1016/j.ekir.2020.04.002.
7) Lazareth H, Péré H, Binois Y, Chabannes M, Schurder J, Bruneau T, et al. COVID-19-related collapsing glomerulopathy in a kidney transplant recipient. Am J Kidney Dis. 2020;76(4):590-4. doi: 10.1053/j.ajkd.2020.06.009.
8) Ahn W, Bomback AS. Approach to diagnosis and management of primary glomerular diseases due to podocytopathies in adults: core curriculum 2020. Am J Kidney Dis. 2020;75(6):955-64. doi: 10.1053/j.ajkd.2019.12.019.
9) Wada T, Nangaku M. A circulating permeability factor in focal segmental glomerulosclerosis: the hunt continues. Clin Kidney J. 2015;8(6):708-15. doi: 10.1093/ckj/sfv090.
10) Lai Q, Spoletini G, Bianco G, Graceffa D, Agnes S, Rossi M, et al. SARS-CoV2 and immunosuppression: A double-edged sword. Transpl Infect Dis. 2020;22(6):e13404. doi: 10.1111/tid.13404.
11) Massoth LR, Desai N, Szabolcs A, Harris CK, Neyaz A, Crotty R, et al. Comparison of RNA in situ hybridization and immunohistochemistry techniques for the detection and localization of SARS-CoV-2 in human tissues. Am J Surg Pathol. 2021;45(1):14-24. doi: 10.1097/PAS.0000000000001563.
12) Lazareth H, Péré H, Binois Y, Chabannes M, Schurder J, Bruneau T, et al. COVID-19-related collapsing glomerulopathy in a kidney transplant recipient. Am J Kidney Dis. 2020;76(4):590-4. doi: 10.1053/j.ajkd.2020.06.009.
13) Sun DQ, Wang TY, Zheng KI, Targher G, Byrne CD, Chen YP, et al. Subclinical acute kidney injury in COVID-19 patients: a retrospective cohort study. Nephron. 2020;144(7):347-50. doi: 10.1159/000508502.
14) Husain-Syed F, Wilhelm J, Kassoumeh S, Birk HW, Herold S, Vadász I, et al. Acute kidney injury and urinary biomarkers in hospitalized patients with coronavirus disease-2019. Nephrol Dial Transplant. 2020;35(7):1271-4. doi: 10.1093/ndt/gfaa162.
Publicado
2021-06-22
Cómo citar
1.
Camargo-Salamanca A, Pinto-Ramírez J, Orozco-de la Hoz C, García-López A, Patino-Jaramillo N, Girón-Luque F. Enfermedad de cambios mínimos como manifestación inicial de COVID-19 en paciente latinoamericano con trasplante renal. Rev Nefrol Dial Traspl. [Internet]. 22 de junio de 2021 [citado 22 de diciembre de 2024];41(2):125-9. Disponible en: http://revistarenal.org.ar/index.php/rndt/article/view/649
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Derechos de autor 2021 Revista de Nefrología, Diálisis y Trasplante
Esta obra está bajo licencia internacional Creative Commons Reconocimiento-NoComercial-CompartirIgual 4.0.
